SARC's Open Sarcoma Trials

SARC currently has the following clinical trials open for patient enrollment:

Click on the study link to read more information such as eligibility criteria and to learn which research centers are actively enrolling patients.


SARC012: A Randomized, Double-Blinded, Placebo-Controlled, Multi-Institutional, Phase II.5 Study of AZD0530, a Selective Src Kinase Inhibitor, In Patients with Recurrent Osteosarcoma Localized to the Lung
PI: Lee J Helman, MD

SARC016: Phase 2 study of the mTOR inhibitor everolimus in combination with bevacizumab in patients with sporadic and neurofibromatosis type 1 (NF1) related refractory malignant peripheral nerve sheath tumors
PI: Brigitte C. Widemann, MD

SARC020: Comparing the efficacy of Trabectedin administered as a 3-hour or 24-hour infusion to doxorubicin in patients with advanced or metastatic untreated soft tissue sarcoma                  
PI: James Butrynski, MD and Binh Bui Nguyen, MD, Ph.D.
SARC021: A Randomized Phase III, multicenter, open-label study comparing  TH-302 in combination with doxorubicin vs. doxorubicin alone in subjects with locally advanced unresectable or metastatic soft tissue sarcoma                  
PI: William, Tap, MD, Memorial Sloan Kettering Cancer Center

SARC022: A Phase II Study of OSI-906 in Patients with Pediatric and Adult Wild Type Gastrointestinal Stromal Tumors                 
PI: Margaret von Mehren, MD, Fox Chase Cancer Center
To see where our sites are located, see our map of sites. is an online database offering up-to-date information to help patients locate clinical trials for a wide range of diseases and conditions, including sarcoma.

This site is coordinated by the National Institutes of Health and contains close to 50,000 trials that are both federally and privately sponsored and conducted in all fifty states, as well as in many other countries.
The purpose and objectives of the study, eligibility criteria, information about a trial’s sponsor and also a list of institutions participating in the trial, can all be found on a study's website listing on